OBJECTIVE To determine the efficacy and safety of nifedipine as tocolytic agent in women with preterm labor
34259466 10
Brand names: Adalat, Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL
Nifedipine is as effective as beta-mimetics in decreasing uterine activity
As more and more families seek
hormone antagonists
nifedipine (first-line) terbutaline (second-line) Close PDA (indomethacin) Sympathetic symptoms (anxiety
Nifedipine was associated with a significant reduction in the risk of delivery within 7 days of initiation of
Higher doses (20–30 mg tid–qid) may be required, depending on patient response
Our study aimed to examine if adjunctive nifedipine administration influences neurodevelopment outcome in TTTS pregnancies complicated
The use of nifedipine during the postpartum period in patients with severe
7 vs
The mean maternal serum concentration of nifedipine before birth was 38
Heersink School of Medicine, University of OBSTETRICS Nifedipine in the management of preterm labor: a systematic review and metaanalysis Agustín Conde-Agudelo, MD, MPH; Roberto Romero, MD; Juan Pedro Kusanovic, MD Conde-Agudelo A, Romero R, Kusanovic JP
It is taken once a day, with or without food
Our data indicated that nifedipine decreased the systolic pressure the most at 20 min post-first dose (difference from the first measurement to the second measurement) as much as 13
Intravenous Labetalol and IV Hydralazine are considered first line drugs of choice
The frequency of primary outcome attainment was high and maternal adverse events were low in all three treatment groups
It is primarily used as an antihypertensive and as an anti-anginal medication
We compared rates of hospital readmission for hypertension between patients discharged postpartum on labetalol alone, nifedipine alone, or combined nifedipine and labetalol
The review was generally well conducted, but the authors’ conclusions regarding magnesium sulphate
Betablockers — deterioration of heart failure has been observed in isolated cases
3 hours
Results: In our study, we found that there was a strong statistical significance in stabilizing the BP with oral nifedipine than with intravenous labetalol drug used